Science Discoveries

Adipose tissue-derived mesenchymal stem cells improve revascularization outcomes to restore renal function in swine atherosclerotic renal artery stenosis. - 09-26-2012

Renal artery stenosis is a narrowing of the arteries that supply blood from the heart to the kidneys. When the renal arteries decrease in width, blood flow to the kidneys is restricted. High blood pressure is a common result of renal artery stenosis that affects only one of the arteries.

This study in pigs found that injecting a type of stem cells into the kidneys improved the response to angioplasty. Further studies are needed to better understand this mechanism in pigs and eventually humans.

CTSA Support

The Mayo Center for Translational Science Activities supports the Immunochemical Core which performed lipid panel analysis for this study.