Akiko Yabuuchi, a Ph.D. in George Daley's lab at Children's Hospital Boston, conducts stem cell research inside a clean room. Daley is a faculty member at Harvard Medical School and part of the Harvard Stem Cell Institute.

Harvard University

Cambridge, MA

Principal Investigator: Lee Nadler

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Participating Institutions and Community Partners
Harvard Affiliated Academic Health Care Institutions
Beth Israel-Deaconess Medical Center
Brigham and Women's Hospital
Children's Hospital Boston
Dana-Farber Cancer Institute
Forsyth Institute
Joslin Diabetes Center
Massachusetts Eye and Ear Infirmary
Massachusetts General Hospital
McLean Hospital
Mount Auburn Hospital
Schepens Eye Research Institute
Spaulding Rehabilitation Hospital
VA Boston Healthcare System
Collaborative Academic Institutions
Massachusetts Institute of Technology
Broad Institute
Community Healthcare Institutions
Cambridge Health Alliance
Harvard Medical School Department of Ambulatory Care and Prevention at Harvard Pilgrim Healthcare
Harvard University
Harvard Medical School
Harvard School of Dental Medicine
Harvard School of Public Health
Harvard University Faculty of Arts and Sciences
Harvard School of Engineering and Applied Sciences
Harvard Business School
Harvard Law School
Harvard Divinity School
Kennedy School of Government
Harvard Graduate School of Education
Radcliffe Institute for Advanced Study

The Harvard Clinical and Translational Science Center will alter the culture of clinical and translational research at Harvard by creating structured and effective methods to connect and support individual investigators and teams of investigators. The center will create managed approaches to focusing the skills of experts in diverse disciplines to find innovative solutions to challenging questions in clinical and translational research. It will deploy both new and old resources more effectively, lowering the barriers to the initiation and conduct of clinical and translational research within and across institutions. In parallel, the center will build a structure to encourage initiation of new clinical and translational research projects and provide mechanisms for bringing together interdisciplinary and cross-institutional teams, opening the doors of the clinical and translational research enterprise to researchers and engineers with diverse backgrounds, skills, and resources. The center will educate the broader Harvard research community on the opportunities, challenges, and goals of clinical and translational research. The overarching goals focus on the individual development of clinical and translational researchers and alignment of incentives with desired outcomes. Structured processes will be created that will enhance the ability of investigators to identify information, seek expertise, and access tools necessary to conceive and successfully complete clinical and translational experiments.


Lee Nadler

Intern, Resident, Columbia Presbyterian; Fellow in Medical Oncology Dana-Farber(DFCI); Chief of Hemat Malig DFCI; Chief Med Oncol Brigham and Women's Hospital; Sr VP Experimental Medicine DFCI, Director Center for CTR DFCI

Research Interests

Lee Nadler

Immunotherapy of hematologic malignancies (esp. lymphomas), bone marrow transplantation in lymphoma.

Lori Shridhare

617 432-7808
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